Sickness and Abnormal Behaviors as Indicators of Animal Suffering
Abstract
The welfare status of an animal represents the integrated outcome of all sensory and other neural inputs from within its body and from the environment. These inputs are processed and interpreted by the animal’s brain according to its species-specific and individual nature and experiences, and then are perceived consciously. That being said, for an animal to be able to perceive states that we believe would reflect its welfare, the animal must be alive and conscious, and it must also be sentient. Previous studies, which I cite and describe further later in this paper, show that the brains of animals, especially mammals, have enough complexity to process mental states. The mental abilities of an animal arise as a result of sensory and other neural inputs linked to nutritional, environmental, health and behavioral components of physical or functional abilities. They are also linked to cognitive-neural inputs and activity related to external challenge. All of these components are integrated and expressed mentally as varying degrees of thirst, hunger, weakness, debility, breathlessness, nausea, sickness, pain, distress, fear, anxiety, helplessness, boredom and so on.
Keywords
Full Text:
PDFReferences
Anisman, Hymie, and Zul Merali. 2002. “Cytokines, Stress, and Depressive Illness”. Brain, Behavior and Immunology 16 (5): 513-24. doi: 10.1016/S08891591(02)00009-0.
Banks, William A., Abba J. Kastin, and Debra A. Durham. 1989. “Bidirectional Transport of Interleukin-1 Alpha across the Blood Brain Barrier”. Brain Research Bulletin 23 (6): 433-7. doi: 10.1016/0361-9230(89)90185-8.
Banks, William A., et al. 1991. “Human Interleukin (IL) 1α, Murine IL-1α and Murine IL-1β Are Transported from Blood to Brain in the Mouse by a Shared Saturable Mechanism”. Journal of Pharmacology and Experimental Therapeutics 259 (3): 988-96.
Barbieri, Sara, and Caludia Nassuato, eds. 2006. Basic Information for the Development of the Animal Welfare. Risk Assessment Guidelines (EFSA/AHAW/2006/01). Parma: EFSA. Broom, Donald M. 1991. “Assessing Welfare and Suffering”. Behavioural Processes 25 (2-3): 117-23. doi: 10.1016/0376-6357(91)90014-Q.
Broom, Donald M., and Kenneth G. Johnson. 1993. Stress and Animal Welfare. London: Chapman and Hall.
Cronin, Gregory M., Pieter R. Wiepkema, and Gert J. Hofstede. 1984. “The Development of Stereotypies in Tethered Sows”. In Proceedings of the International Congress on Applied Ethology in Farm Animals, edited by Jürgen Unshelm, Gerrit van Putten, Klaus Zeeb, and Ingvar Eksebo, 97-100. Kiel, Germany: KTBL Darmstadt.
Dantzer, Robert. 1991. “Stress, Stereotypies and Welfare”. Behavioural Processes 25
(2-3): 95-102. doi: 10.1016/0376-6357(91)90012-O. 2001. “Cytokine-induced Sickness Behavior: Where Do We Stand?”. Brain, Behavior, and Immunity 15 (1): 1-18. doi: 10.1006/brbi.2000.0613.
Deak, Terrence, et al. 1997. “Evidence That Brief Stress May Induce the Acute Phase Response in Rats”. American Journal of Physiology 273 (6-2): R1998-2004.
Dinan, Timothy G. 1994. “Glucocorticoids and the Genesis of Depressive Illness. A Psychobiological Model”. The British Journal of Psychiatry 164: 365-71. doi: 10.1192/bjp.164.3.365.
Dunn, Adrian J., and Artur H. Swiergiel. 1998. “The Role of Cytokines in Infectionrelated Behavior”. Annals of the New York Academy of Sciences 840: 577-85. doi: 10.1111/j.1749-6632.1998.tb09596.x.
EFSA. 2005. “Opinion of the Scientific Panel AHAW Related to the Aspects of the Biology and Welfare of Animals Used for Experimental and Other Scientific Purpose (EFSA-Q-2004-105)”. European Food Safety Agency Journal 292: 1-136.
Fitzgerald, Marie. 1999. “Development and Neurobiology of Pain”. In Textbook of Pain. 4th edition, edited by P.D. Wall and R.D. Melzack, 235-51. Edinburgh, UK: Churchill Livingstone.
Friedman, Alon, et al. 1996. “Pyridostigmine Brain Penetration under Stress Enhances Neuronal Excitability and Induces Early Immediate Transcriptional Response”. Nature Medicine 2: 1382-5. doi: 10.1038/nm1296-1382.
Goujon, E., et al. 1995. “Stress Downregulates Lipopolysaccharide-induced Expression of Proinflammatory Cytokines in the Spleen, Pituitary, and Brain of Mice”. Brain, Behavior, and Immunity 9 (4): 292-303. doi: 10.1006/brbi.1995.1028.
Hart, Benjamin L. 1988. “Biological Basis of the Behaviour of Sick Animals”. Neuroscience & Biobehavioral Reviews 12 (2): 123-37. doi: 10.1016/S0149-7634(88)80004-6.
Hopkins, Stephen J., and Nancy J. Rothwell. 1995. “Cytokines and the Nervous System I: Expression and Recognition”. Trends in Neurosciences 18 (2): 83-8. doi: 10.1016/0166-2236(95)93881-W.
Lemay, Lin G., Arthur J. Vander, and Matthew J. Kluger. 1990. “The Effect of Psychological Stress on Plasma Interleukin-6 Activity in Rats”. Physiology & Behavior 47 (5): 957-61. doi: 10.1016/0031-9384(90)90024-X.
Leonard, Brian E., and Cai Song. 1996. “Stress and the Immune System in the Etiology of Anxiety and Depression”. Pharmacology Biochemistry and Behavior 54 (1): 299-303. doi: 10.1016/0091-3057(95)02158-2.
McEwen, Bruce S. 2000. “Allostasis and Allostatic Load Implications for Neuropsychopharmacology”. Neuropsychopharmacology 22: 108-24. doi: 10.1016/S0893133X(99)00129-3.
McEwen, Bruce S., and John C. Wingfield. 2003. “The Concept of Allostasis in Biology and Medicine”. Hormones and Behavior 43 (1): 2-15. doi: 10.1016/S0018506X(02)00024-7.
Minami, Masabumi, et al. 1991. “Immobilization Stress Induces Interleukin-l mRNA in the Rat Hypothalamus”. Neuroscience Letters 123 (2): 254-6. doi: 10.1016/03043940(91)90944-O.
Ottaviani, Enzo, and Claudio Franceschi. 1998. “A New Theory on the Common Evolutionary Origin of Natural Immunity, Inflammation and Stress Response: the Invertebrate Phagocytic Immunocyte as an Eye-witness”. Domestic Animal Endocrinology 15 (5): 291-6. doi: 10.1016/S0739-7240(98)00021-6.
Ovadia, Haim, et al. 2001. “Evaluation of the Effect of Stress on the Blood-brain Barrier: Critical Role of the Brain Perfusion Time”. Brain Research 905 (1-1): 21-5. doi: 10.1016/S0006-8993(01)02361-7.
Owens, Michael J., and Charles B. Nemeroff. 1991. “Physiology and Pharmacology of Corticotropin-releasing Factor”. Pharmacological Reviews 43 (4): 425-73.
Plotkin, Scott. R., et al. 2000. “Differential Transport of Rat and Human Interleukin-1α across the Blood-brain Barrier and Blood-testis Barrier in Rats”. Brain Research 881 (1): 57-61. doi: 10.1016/S0006-8993(00)02772-4.
Ravtndran, Arun V., et al. 1995. “Lymphocyte Subset in Major Depression and Dysthymia: Modification by Antidepressant Treatment”. Psychosomatic Medicine 57 (6): 555-63.
Ravtndran, Arun V., et al. 1999. “Treatment of Primary Dysthymia with Group Cognitive Therapy and Pharmacotherapy: Clinical Symptoms and Functional Impairments”. American Journal of Psychiatry 156 (10): 1608-17.
Schöbitz, Bernd, Florian Holsboer, and Ronald E. de Kloet. 1994. “Cytokines in the Healthy and Diseased Brain”. News in Physiological Sciences 9 (3): 138-42.
Shintani, F., et al. 1995. “Involvement of Interleukin-1 in Immobilization Stress-Induced Increase in Plasma Adrenocorticotropic Hormones and in Release of Hypothalamic Monoamines in Rat”. Journal of Neuroscience 15 (3-1): 1961-70.
Smidt, Diedrich, ed. 1983. Indicators Relevant to Farm animal Welfare. A Seminar in the CEC Programme of Coordination of Research on Animal Welfare, Organized by Dr. D. Smidt, and Held in Mariensee, 9-10 November 1982. Dordrecht, The Netherlands: Kluwer Academic Publishers.
Squires, James E. 2003. Applied Animal Endocrinology. Wallingford: CABI Publishing.
Veissier, Isabelle, et al. 2000. “Welfare of Livestock: How to Define and Evaluate?”. Developmental Medicine and Child Neurology 31 (205): 117-24.
Webster, John. 2005. Animal Welfare: Limping towards Eden. Oxford: Blackwell Publishing.
Wechsler, Beat. 1995. “Coping and Coping Strategies: a Behavioural View”. Applied Animal Behaviour Science 43 (2):123-34. doi: 10.1016/0168-1591(95)00557-9.
Wiepkema, Pieter R. 1987. “Behavioural Aspects of Stress”. In The Biology of Stress in Farm Animals: an Integrated Approach. Current Topics in Veterinary Medicine and Animal Science, edited by Pieter R. Wiepkema and Pieter W.M. van Adrichem, 113-38. The Hague, The Netherlands: Martinus Nijhoff.
DOI: https://doi.org/10.7358/rela-2013-001-panz
Copyright (©) 2018 Michele Panzera – Editorial format and Graphical layout: copyright (©) LED Edizioni Universitarie
Relations. Beyond Anthropocentrism
Registered by Tribunale di Milano (04/05/2012 n. 211)
Online ISSN 2280-9643 - Print ISSN 2283-3196
Executive Editor: Francesco Allegri
Associate Editor: Matteo Andreozzi
Review Editors: Sofia Bonicalzi - Eleonora Adorni
Editorial Board: Ralph R. Acampora - Carol J. Adams - Vilma Baricalla - Luisella Battaglia - Rod Bennison - Matthew R. Calarco - Piergiorgio Donatelli - William Grove-Fanning - Serenella Iovino - Luigi Lombardi Vallauri - Christoph Lumer - Joel MacClellan - Dario Martinelli - Roberto Marchesini - Alma Massaro - Serpil Oppermann - Simone Pollo - Paola Sobbrio - Kim Stallwood - Sabrina Tonutti - Jessica Ullrich - Federico Zuolo
Referee List
© 2001 LED Edizioni Universitarie di Lettere Economia Diritto